Arcoflow platform

Our solution is composed of a novel biological assay enabling the molecular mode of action identification directly in any primary cell, embedded in a microfluidic device.

Our microfluidic technology:

  • accelerates the assay (20 min),

  • decrease the amount of reagents needed (2 uL volume chamber),

  • standardizes the entire assay (integration of the microfluidics in standard 384 well plate)

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Features

  • Close-up of a white circular object with a light blue glow along the edge, featuring a stylized orange snowflake and circular design in the center.

    Primary cells

    Our new biological assay allows us to test any mammalian cell and preserves the native environment of the GPCR

  • Digital illustration with blue and white curved shapes and a circular outline, resembling a modern, abstract design.

    G protein determination

    We determine which G protein is involved in the GPCR activation (i.e. molecular mode of action)

  • A blue digital 3D representation of a computer chip or circuit board with a grid-like pattern, viewed inside a glowing white and blue gradient sphere with an arrow pointing downward.

    Microfluidic well plate

    Our assay is embeded in custom microfluidic 384 well plate

  • Close-up of a speaker on a distortion meter panel, with the circular gauge showing a red zone and a needle pointing towards it.

    Fluorescence

    Our simple fluorescent read out allows us to directly detect the GPCR activation

Workflow

  • Illustration of a molecule on the left and a neuron on the right with a plus sign between them, and a number 1 below.

    Compounds to be tested & primary cells

  • A digital illustration of a laboratory pipette tip rack with three bottles of liquid in the background.

    Arcoflow well plate & reagents

  • A visualization of a network or molecule with a central node connected to five smaller nodes, all in shades of pink and red, with a blue glow around a white circle labeled '3' at the bottom.

    Mode of action & identification of promising compounds

  • Minimalist illustration of a pink pig resting on its belly with a small black eye, a tiny black nose, and a light pink tail, and a glowing white circle with the number four below the pig.

    Promising compounds moved to preclinical

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We are driven by our passion for what we do